Organo-Metalloid Compounds
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Filtered Search Results
Medchemexpress LLC Azido-PEG3-SS-PEG3-azide | 1310827-27-0 | 99.3% | 468.59 | 50 MG
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Azido-PEG3-SS-PEG3-azide is a PEG-based PROTAC linker designed for use in the synthesis of PROTACs. This compound functions as a click chemistry reagent, featuring an Azide group that can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with molecules containing Alkyne groups. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. PROTACs themselves are agents that utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- A PEG-based PROTAC linker.
- Used in the synthesis of PROTACs.
- Functions as a click chemistry reagent.
- Contains an Azide group.
- Can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with Alkyne-containing molecules.
- Can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN-containing molecules.
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Medchemexpress LLC Ms-PEG5-t-butyl ester | 870487-48-2 | C16H32O9S | 50 MG
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Ms-PEG5-t-butyl ester is a PEG-based PROTAC linker primarily used in the synthesis of PROTACs.
- PROTACs contain two different ligands connected by a linker.
- One ligand is for an E3 ubiquitin ligase, and the other is for the target protein.
- PROTACs exploit the intracellular ubiquitin-proteasome system.
- Used to selectively degrade target proteins.
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![Medchemexpress LLC 2-[2-(2-methoxyethoxy)ethoxy]ethyl 4-methylbenzene-1-sulfonate | 62921-74-8 | MFCD06200731 | 98.8% | 318.39 g/mol | C14H22O6S | 500 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000210386.png-250.jpg)
Medchemexpress LLC 2-[2-(2-methoxyethoxy)ethoxy]ethyl 4-methylbenzene-1-sulfonate | 62921-74-8 | MFCD06200731 | 98.8% | 318.39 g/mol | C14H22O6S | 500 MG
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m-PEG3-Tos is a tosyl-terminated polyethylene glycol (PEG) linker used as a reactive PEG3 spacer for conjugation and PROTAC synthesis. The tosyl leaving group enables nucleophilic substitution reactions to attach functional groups or linker arms in medicinal chemistry and bioconjugation workflows.
- Tosyl-terminated PEG3 linker for conjugation and PROTAC synthesis.
- Chemical name: 2-[2-(2-methoxyethoxy)ethoxy]ethyl 4-methylbenzene-1-sulfonate.
- CAS number: 62921-74-8.
- Molecular formula: C14H22O6S.
- Molecular weight: 318.39 g/mol.
- Purity: 98.8%.
- Package size: 500 MG.
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Medchemexpress LLC Azido-PEG5-alcohol | 86770-68-5 | >97.0% | 263.29 g·mol⁻¹ | C10H21N3O5 | 5 G
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Azido-PEG5-alcohol is an azide-terminated polyethylene glycol linker containing five ethylene glycol units and a terminal primary alcohol, used as a water-soluble reagent for bioconjugation and linker synthesis. It is commonly applied in click chemistry and in the construction of antibody-drug conjugates and PROTACs.
- Azide functionality enables CuAAC and SPAAC click reactions.
- Water-soluble PEG5 spacer improves solubility and flexibility.
- Terminal primary alcohol provides a synthetic handle for derivatization.
- Suitable for ADC linker synthesis and PROTAC construction.
- Supplied as a solid with reported purity >97.0%.
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Medchemexpress LLC M-PEG5-Br | 854601-80-2 | 98.0% | C11H23BrO5 | 5 G
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m-PEG5-Br is a PEG-based PROTAC linker. It is for research use only and not for sale to patients. This linker can be used in the synthesis of PROTACs, which consist of two different ligands connected by a linker; one ligand is for an E3 ubiquitin ligase and the other is for the target protein. PROTACs utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Used in the synthesis of PROTACs
- Utilizes the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- For research use only
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![eMolecules 546-68-9 | Tetraisopropyl orthotitanate | Chem-Impex | MFCD00008871 | 284.219 | C12H28O4Ti | 27.000 | [Ti+4].CC(C)[O-].CC(C)[O-].CC(C)[O-].CC(C)[O-] | 1kg | 686070057](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000126441.jpg-250.jpg)
eMolecules 546-68-9 | Tetraisopropyl orthotitanate | Chem-Impex | MFCD00008871 | 284.219 | C12H28O4Ti | 27.000 | [Ti+4].CC(C)[O-].CC(C)[O-].CC(C)[O-].CC(C)[O-] | 1kg | 686070057
Tetraisopropyl orthotitanate | Chem-Impex | 546-68-9 | MFCD00008871 | 284.219 | C12H28O4Ti | 27.000 | [Ti+4].CC(C)[O-].CC(C)[O-].CC(C)[O-].CC(C)[O-] | 1kg | 686070057
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Medchemexpress LLC (S,R,S)-AHPC-PEG3-NH2 hydrochloride | 2097971-11-2 | MFCD31656714 | 99.0% | 656.23 g/mol | C30H46ClN5O7S | 1 G
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(S,R,S)-AHPC-PEG3-NH2 hydrochloride is a VHL E3 ligase ligand-linker conjugate that combines a stereodefined AHPC VHL ligand with a three-unit polyethylene glycol linker terminating in a primary amine. Supplied as the hydrochloride salt, it is intended as a research building block for PROTAC synthesis and other chemical biology applications.
- Hydrochloride salt form for improved handling.
- Primary amine terminus suitable for common coupling chemistries.
- Three-unit PEG linker provides aqueous solubility and flexible spacing.
- Stereochemically defined (S,R,S) VHL ligand for targeted E3 ligase engagement.
- High reported purity (~99.0%) for reliable synthetic use.
- Available in small to gram-scale quantities for research workflows.
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Medchemexpress LLC (S,R,S)-AHPC-C6-PEG3-C4-Cl | 1835705-55-9 | MFCD31560478 | 97.0% | 751.42 | C38H59ClN4O7S | 1 G
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(S,R,S)-AHPC-C6-PEG3-C4-Cl is a VHL ligand-linker conjugate designed as a building block for PROTAC synthesis and ligand-linker conjugate development in targeted protein degradation research. It contains an (S,R,S)-configured AHPC VHL ligand connected via a six-carbon PEG3 linker with a terminal chloro group to enable downstream conjugation.
- Useful as a VHL (E3 ligase) ligand building block for degrader design.
- C6-PEG3 linker provides flexibility and spacer length for bifunctional molecules.
- Terminal chloro group enables nucleophilic substitution or further functionalization.
- Characterized by analytical data including HPLC and LC-MS for batch confirmation.
- Provided as a solid suitable for synthetic chemistry workflows and storage under controlled conditions.
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Medchemexpress LLC Boc-NH-PEG3-propargyl | 1333880-60-6 | 97.0% | C14H25NO5 | 100 MG
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Boc-NH-PEG3-propargyl is a PEG-based PROTAC linker designed for the synthesis of PROTACs. It functions as a click chemistry reagent, featuring an Alkyne group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules.
- Used in PROTAC synthesis
- Functions as a click chemistry reagent
- Contains an Alkyne group
- Enables copper-catalyzed azide-alkyne cycloaddition with azide-containing molecules
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Medchemexpress LLC m-PEG3-succinimidyl carbonate | 477775-77-2 | 99.4% | C12H19NO8 | 100 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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m-PEG3-succinimidyl carbonate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Contains two different ligands connected by a linker
- One ligand for an E3 ubiquitin ligase
- The other ligand for the target protein
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
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Medchemexpress LLC 2-(2-(2-bromoethoxy)ethoxy)ethyl methanesulfonate | 2702323-73-5 | 95.0% | C7H15BrO5S | 10MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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A PEG-based bifunctional linker with a bromide and a methanesulfonate functional group, designed for use in the synthesis and assembly of PROTAC molecules. It provides a short, flexible PEG3 spacer to connect ligands while enabling nucleophilic substitution chemistry.
- Provides a short PEG3 spacer for flexibility and solubility.
- Contains terminal bromide and methanesulfonate groups that act as leaving groups for conjugation.
- Suitable for linker assembly and PROTAC synthesis via nucleophilic substitution.
- High research-grade purity for consistent performance.
- Available in small research sizes and supplied as a liquid for ease of handling.
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eMolecules 65094-22-6 | Bromodifluoromethyl diethylphosphonate | Combi-Blocks, Inc. | MFCD00069118 | 267.007 | C5H10BrF2O3P | 95.000 | CCOP(=O)(OCC)C(F)(F)Br | 1kg | 873647984
Bromodifluoromethyl diethylphosphonate | Combi-Blocks, Inc. | 65094-22-6 | MFCD00069118 | 267.007 | C5H10BrF2O3P | 95.000 | CCOP(=O)(OCC)C(F)(F)Br | 1kg | 873647984
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![eMolecules 65094-22-6 | 1-[[bromo(difluoro)methyl]-ethoxy-phosphoryl]oxyethane | Pharmablock | MFCD00069118 | 267.007 | C5H10BrF2O3P | 97.000 | CCOP(=O)(OCC)C(F)(F)Br | 2.5g | 686926920](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000490911.jpg-250.jpg)
eMolecules 65094-22-6 | 1-[[bromo(difluoro)methyl]-ethoxy-phosphoryl]oxyethane | Pharmablock | MFCD00069118 | 267.007 | C5H10BrF2O3P | 97.000 | CCOP(=O)(OCC)C(F)(F)Br | 2.5g | 686926920
1-[[bromo(difluoro)methyl]-ethoxy-phosphoryl]oxyethane | Pharmablock | 65094-22-6 | MFCD00069118 | 267.007 | C5H10BrF2O3P | 97.000 | CCOP(=O)(OCC)C(F)(F)Br | 2.5g | 686926920
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eMolecules 930-30-3 | Cyclopent-2-enone | Oakwood Chemicals | MFCD00001401 | 82.102 | C5H6O | 96.000 | O=C1CCC=C1 | 1g | 480134567
Cyclopent-2-enone | Oakwood Chemicals | 930-30-3 | MFCD00001401 | 82.102 | C5H6O | 96.000 | O=C1CCC=C1 | 1g | 480134567
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Aobchem 1-(Cyclopent-1-en-1-yl)-2-isopropoxybenzene | 97% | CAS 2901081-81-8 | C14H18O | 250mg
1-(Cyclopent-1-en-1-yl)-2-isopropoxybenzene | 97% | CAS 2901081-81-8 | C14H18O | 250mg
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